Reversible Neutrophil Abnormalities Related to Supratherapeutic Valproic Acid Levels
نویسندگان
چکیده
منابع مشابه
Ammonia Blood Levels and Valproic Acid
The prevalence and magnitude of valproic acid (VPA)-related hyperammonemia (HA) were estimated by a review of the literature, and the clinical symptomatology and risk factors for the development of HA determined by researchers at university hospitals in Santiago, Chile; and Rush University Medical Center, Chicago, IL. Out of 183 studies between 1980 and 2005, 24 met inclusion criteria; 7 were p...
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Valproic acid is a new antiepileptic drug recently introduced in the United States for the treatment of absence seizures. In this study on patients with absence and other seizure types, the majority of patients achieved optimal control within four weeks of therapy. No patient responded to valproic acid who did not show an initial clinical response by four weeks of active therapy. Optimal respon...
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WARNINGS: LIFE THREATENING ADVERSE REACTIONS See full prescribing information for complete boxed warning. Hepato toxicity, including fatalities, usually during first 6 months o f treatment. Children under the age of two years and patients with mitochondrial disorders are at higher risk. Monitor patients c losely, and perform serum liver testing prior to therapy and at frequent intervals thereaf...
متن کاملPlasma ammonia levels in patients treated with valproic acid
10.4172/Neuropsychiatry.1000178 © 2017 pISSN 1758-2008 eISSN 1758-2016 Neuropsychiatry (London) (2017) 7(1), 42–47 42 1Department of Psychiatry, University of Occupational and Environmental Health, Fukuoka, Japan †Author for correspondence: Prof. Reiji Yoshimura, Department of Psychiatry, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka 807...
متن کاملValproic acid and plasma levels of primidone and derived phenobarbital.
Five patients were studied to determine whether kinetic interaction occurs between valproic acid and primidone. During concurrent administration of primidone and valproic acid no significant interaction was observed. Primidone and derived phenobarbital levels did not change significantly. No adjustment of primidone dose was required when valproic acid was used as adjunctive therapy.
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ژورنال
عنوان ژورنال: Mayo Clinic Proceedings
سال: 2008
ISSN: 0025-6196
DOI: 10.4065/83.5.600